Peter K Henke Selected Research

P-Selectin

1/2016	Gram-Negative Pneumonia Alters Large-Vein Cell-Adhesion Molecule Profile and Potentiates Experimental Stasis Venous Thrombosis.
4/2015	P-selectin inhibition therapeutically promotes thrombus resolution and prevents vein wall fibrosis better than enoxaparin and an inhibitor to von Willebrand factor.
6/2013	The electrolytic inferior vena cava model (EIM) to study thrombogenesis and thrombus resolution with continuous blood flow in the mouse.
4/2013	Soluble P-selectin for the diagnosis of lower extremity deep venous thrombosis.
8/2011	Evaluation of soluble P-selectin as a marker for the diagnosis of deep venous thrombosis.
1/2011	Postthrombotic vein wall remodeling: preliminary observations.
4/2010	P-selectin/ PSGL-1 inhibitors versus enoxaparin in the resolution of venous thrombosis: a meta-analysis.
1/2010	Aging is associated with impaired thrombus resolution in a mouse model of stasis induced thrombosis.
4/2009	Leukocyte- and platelet-derived microparticles correlate with thrombus weight and tissue factor activity in an experimental mouse model of venous thrombosis.
3/2007	Resolution of venous thrombosis using a novel oral small-molecule inhibitor of P-selectin (PSI-697) without anticoagulation.

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Peter K Henke Research Topics

Disease

55	Thrombosis (Thrombus) 01/2022 - 05/2002
48	Venous Thrombosis (Deep-Vein Thrombosis) 01/2022 - 11/2002
18	Abdominal Aortic Aneurysm 01/2021 - 02/2002
14	Fibrosis (Cirrhosis) 01/2022 - 11/2002
14	Inflammation (Inflammations) 01/2021 - 06/2003
13	Myocardial Infarction 01/2021 - 03/2003
12	Venous Thromboembolism 12/2022 - 09/2002
12	Aneurysm (Aneurysms) 04/2015 - 08/2004
11	Wounds and Injuries (Trauma) 01/2019 - 06/2005
9	Hemorrhage 01/2021 - 11/2005
8	Renal Insufficiency (Renal Failure) 01/2017 - 05/2002
8	Neoplasms (Cancer) 10/2012 - 05/2003
6	Pathologic Constriction (Stenosis) 02/2020 - 01/2006
6	Heart Failure 01/2020 - 02/2004
6	Stroke (Strokes) 01/2018 - 01/2004
5	Chronic Limb-Threatening Ischemia 11/2019 - 08/2013
5	Anemia 01/2018 - 12/2014
5	Peripheral Arterial Disease 01/2016 - 08/2011
4	Venous Insufficiency 01/2021 - 09/2005
4	Pneumonia (Pneumonitis) 01/2021 - 02/2007
4	Aortic Aneurysm (Aneurysm, Aortic) 01/2020 - 08/2004
4	Neutropenia 01/2017 - 05/2003
4	Chronic Obstructive Pulmonary Disease (COPD) 01/2016 - 03/2003
4	Ischemia 03/2009 - 02/2002
3	Postthrombotic Syndrome 01/2021 - 02/2011
3	Pulmonary Embolism 01/2021 - 09/2002
3	Vascular Diseases (Vascular Disease) 01/2020 - 02/2004
3	Diabetes Mellitus 01/2020 - 05/2002
3	Coronary Artery Disease (Coronary Atherosclerosis) 01/2020 - 05/2002
3	Hypertension (High Blood Pressure) 01/2017 - 12/2006
3	Pain (Aches) 06/2010 - 05/2002
3	Aortic Dissection 10/2006 - 10/2002
2	Hyperplasia 01/2021 - 04/2006
2	COVID-19 01/2021 - 01/2021
2	Critical Illness (Critically Ill) 01/2021 - 01/2019
2	Cicatrix (Scar) 01/2021 - 01/2015
2	Leukemia 01/2020 - 01/2019

Drug/Important Bio-Agent (IBA)

18	P-SelectinIBA 01/2016 - 09/2002
16	Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA 01/2022 - 11/2002
14	Matrix Metalloproteinases (MMPs)IBA 11/2013 - 08/2004
13	CollagenIBA 01/2018 - 08/2003
10	Proteins (Proteins, Gene)FDA Link 03/2015 - 06/2003
8	AnticoagulantsIBA 01/2021 - 11/2002
8	CytokinesIBA 01/2019 - 09/2002
8	Pancreatic Elastase (Elastase)IBA 11/2016 - 08/2004
8	EnzymesIBA 09/2006 - 11/2002
6	fibrin fragment D (D-dimer)IBA 01/2021 - 12/2005
6	Histones (Histone)IBA 01/2020 - 04/2015
6	Plasminogen Activators (Plasminogen Activator)IBA 01/2015 - 10/2007
6	ImmunosorbentsIBA 09/2006 - 11/2002
5	Heparin (Liquaemin)FDA LinkGeneric 01/2021 - 09/2003
5	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 01/2018 - 06/2003
5	Plasminogen Activator Inhibitor 1IBA 10/2014 - 12/2010
4	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2021 - 02/2004
4	Toll-Like Receptor 9IBA 03/2020 - 01/2011
4	InterleukinsIBA 01/2018 - 08/2005
4	CreatinineIBA 06/2017 - 01/2007
4	E-SelectinIBA 01/2017 - 09/2002
4	Enoxaparin (Lovenox)FDA LinkGeneric 01/2017 - 02/2010
4	Thromboplastin (Tissue Factor)IBA 01/2015 - 11/2002
4	Urokinase-Type Plasminogen Activator (Urokinase)FDA Link 10/2012 - 10/2007
4	Fibrinolysin FDA Link 10/2012 - 10/2007
4	ChemokinesIBA 01/2009 - 09/2002
3	Phenobarbital (Luminal)FDA Link 01/2022 - 03/2008
3	Fibrinogen (Factor I)FDA Link 01/2021 - 03/2009
3	Tissue Plasminogen Activator (Alteplase)FDA Link 01/2021 - 04/2006
3	Biological ProductsIBA 11/2020 - 09/2005
3	Biomarkers (Surrogate Marker)IBA 01/2020 - 08/2011
3	Lysine (L-Lysine)FDA Link 01/2020 - 01/2017
3	Histone MethyltransferasesIBA 01/2019 - 01/2017
3	InterferonsIBA 01/2019 - 12/2010
3	LigandsIBA 01/2017 - 08/2005
3	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 10/2014 - 05/2013
3	Matrix Metalloproteinase 9 (Gelatinase B)IBA 09/2013 - 07/2005
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 02/2010 - 10/2007
3	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 11/2007 - 04/2006
3	2- (4- chlorobenzyl)- 3- hydroxy- 7,8,9,10- tetrahydrobenzo(H)quinoline- 4- carboxylic acidIBA 03/2007 - 08/2005
2	Interleukin-6 (Interleukin 6)IBA 01/2022 - 03/2015
2	Peroxidase (Myeloperoxidase)IBA 01/2021 - 01/2015
2	histone H3 trimethyl Lys4IBA 01/2019 - 01/2017
2	FibrinIBA 01/2018 - 01/2015
2	ElastinIBA 01/2018 - 11/2006

Therapy/Procedure

28	Therapeutics 01/2022 - 05/2003
13	Ligation 01/2022 - 11/2002
13	Surgical Amputation (Amputations) 11/2019 - 05/2002
8	Vascular Surgical Procedures 01/2021 - 01/2004
6	Renal Dialysis (Hemodialysis) 01/2019 - 05/2002
6	Limb Salvage 12/2014 - 02/2004
4	Chemoprevention 12/2022 - 05/2014
4	Catheters 01/2021 - 02/2003
4	Endovascular Procedures 11/2019 - 01/2006
3	Carotid Endarterectomy 01/2021 - 02/2005
3	Endovascular Aneurysm Repair 01/2021 - 04/2015
3	Length of Stay 01/2021 - 01/2004
3	Blood Transfusion (Blood Transfusions) 01/2016 - 02/2007
3	Thrombolytic Therapy 01/2015 - 11/2002
3	Colectomy 10/2012 - 11/2005
2	Aftercare (After-Treatment) 01/2022 - 08/2003
2	Coronary Artery Bypass (Coronary Artery Bypass Surgery) 01/2021 - 11/2005
2	Critical Care (Surgical Intensive Care) 01/2019 - 05/2014